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In neuroscience and psychophysics, an absolute threshold was originally defined as the lowest level of a stimulus – light, sound, touch, etc. – that an organism could detect. Under the influence of signal detection theory , absolute threshold has been redefined as the level at which a stimulus will be detected a specified percentage (often ...
In measuring sensory threshold, noise must be accounted for. Signal noise is defined as the presence of extra, unwanted energy in the observational system which obscures the information of interest. As the measurements come closer to the absolute threshold, the variability of the noise increases, causing the threshold to be obscured. [5]
The tone decay test (also known as the threshold tone decay test or TTDT) is used in audiology to detect and measure auditory fatigue. It was developed by Raymond Carhart in 1957. In people with normal hearing, a tone whose intensity is only slightly above their absolute threshold of hearing can be heard continuously for 60 seconds.
The absolute threshold of hearing (ATH), also known as the absolute hearing threshold or auditory threshold, is the minimum sound level of a pure tone that an average human ear with normal hearing can hear with no other sound present. The absolute threshold relates to the sound that can just be heard by the organism.
In physiology, psychology, or psychophysics, a limen or a liminal point is a sensory threshold of a physiological or psychological response. Such points delineate boundaries of perception; that is, a limen defines a sensory threshold beyond which a particular stimulus becomes perceivable, and below which it remains unperceivable.
The JND is a statistical, rather than an exact quantity: from trial to trial, the difference that a given person notices will vary somewhat, and it is therefore necessary to conduct many trials in order to determine the threshold. The JND usually reported is the difference that a person notices on 50% of trials.
The actual difference is not usually a good way to compare the numbers, in particular because it depends on the unit of measurement. For instance, 1 m is the same as 100 cm, but the absolute difference between 2 and 1 m is 1 while the absolute difference between 200 and 100 cm is 100, giving the impression of a larger difference. [4]
For quality control, one index for the quality of an HTS assay is the magnitude of difference between a positive control and a negative reference in an assay plate. For hit selection, the size of effects of a compound (i.e., a small molecule or an siRNA) is represented by the magnitude of difference between the compound and a negative reference ...