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Cardiotoxicity may be caused by chemotherapy (a usual example is the class of anthracyclines) [3] [4] treatment and/or radiotherapy; [5] complications from anorexia nervosa; adverse effects of heavy metals intake; [6] the long-term abuse of or ingestion at high doses of certain strong stimulants such as cocaine; [7] or an incorrectly ...
In addition to the added potency, the drug has a “low cost,” which leads drug dealers to mix fentanyl with drugs like “heroin, methamphetamine and cocaine, increasing the likelihood of a ...
Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic.It is 30 to 50 times more potent than heroin and 100 times more potent than morphine; [11] its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries.
Speedball, powerball, or over and under [1] is the polydrug mixture of a stimulant with a depressant, usually an opioid.The most well-known mixture used for recreational drug use is that of cocaine and heroin; however, amphetamines can also be mixed with morphine and/or fentanyl.
Alcohol can exacerbate the symptoms and may directly contribute to increased severity of symptoms. The reasons for toxicity vary depending on the mixture of drugs. Usually, most victims die after using two or more drugs in combination that suppress breathing, and the low blood oxygen level causes brain death.
The number of fentanyl-related overdose deaths in North Carolina also has increased each year since 2016, according to the state Department of Health and Human Services. Deaths rose from 442 in ...
Mu receptors have an analgesic effect on the brain, and are found in various parts of the nervous system including the cerebral cortex and thalamus. [16] They can be found in the nucleus accumbens, the pleasure centre of the brain, as well as the amygdala. [16] Kappa receptors, in the hypothalamus, produce a similar analgesic effect.
In New York City, police estimate that 8%, or nearly one in every 10 bags of cocaine sold on the street, contain fentanyl, VICE reported. Here's what you need to know about fentanyl.