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Synovial fluid, also called synovia, is a viscous, non-Newtonian fluid found in the cavities of synovial joints. With its egg white –like consistency, [ 1 ] the principal role of synovial fluid is to reduce friction between the articular cartilage of synovial joints during movement. [ 2 ]
The water of synovial fluid is not secreted as such but is effectively trapped in the joint space by the hyaluronan. The macrophage-like synovial cells (derived from monocytes in blood) [3] are responsible for the removal of undesirable substances from the synovial fluid (hence are rich in Golgi apparatus). It accounts for approximately 25% of ...
These cells represent the main source of hyaluronic acid and also other glycoproteins, major components of the synovial fluid. [ 1 ] [ 2 ] Fibroblast-like synoviocytes are cells of mesenchymal origin that display many characteristics common with fibroblasts , such as expression of several types of collagens and protein vimentin , a part of ...
The synovial cavity/joint is filled with synovial fluid. The joint capsule is made up of an outer layer of fibrous membrane, which keeps the bones together structurally, and an inner layer, the synovial membrane, which seals in the synovial fluid. They are the most common and most movable type of joint in the body of a mammal.
Bursitis is the inflammation of one or more bursae (synovial sacs) of synovial fluid in the body. They are lined with a synovial membrane that secretes a lubricating synovial fluid. [1] There are more than 150 bursae in the human body. [1] The bursae rest at the points where internal functionaries, such as muscles and tendons, slide across bone ...
A synovial bursa, usually simply bursa (pl.: bursae or bursas), is a small fluid-filled sac lined by synovial membrane with an inner capillary layer of viscous synovial fluid (similar in consistency to that of a raw egg white). It provides a cushion between bones and tendons and/or muscles around a joint. This helps to reduce friction between ...
A fluid is defined as a substance that deforms continuously under application of a shearing stress, regardless of how small the stress is. Blood is a primary example of a biological fluid. Air can also be considered as biological fluid as it flows in lungs and the synovial fluid between the knee joints is also an example of a biological fluid.
The average molecular weight in human synovial fluid is 3–4 million Da, and hyaluronic acid purified from human umbilical cord is 3,140,000 Da; [4] other sources mention average molecular weight of 7 million Da for synovial fluid. [3] Hyaluronic acid also contains silicon, ranging 350–1,900 μg/g depending on location in the organism. [39]