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In the 1960s and 1970s, John Vane and others discovered the basic mechanism of aspirin's effects, [3]: 226–231 while clinical trials and other studies from the 1960s to the 1980s established aspirin's efficacy as an anti-clotting agent that reduces the risk of clotting diseases.
Aspirin is the genericized trademark for acetylsalicylic acid ... In the 1960s and 1970s, John Vane and others discovered the basic mechanism of aspirin's effects, ...
Edward Stone was born in Princes Risborough, Buckinghamshire, England, in 1702.His parents were Edward Stone, a gentleman farmer, and his first wife Elizabeth Reynolds. His mother having died, his father took a second wife, Elizabeth Grubb, in 1707; the Grubb family was to play a major role in Stone's li
Sir John Robert Vane FRS (29 March 1927 – 19 November 2004) [1] was a British pharmacologist who was instrumental in the understanding of how aspirin produces pain-relief and anti-inflammatory effects and his work led to new treatments for heart and blood vessel disease and introduction of ACE inhibitors.
A new DNA test suggests they might have even self-prescribed an early version of a common modern day painkiller.
Felix Hoffmann (21 January 1868 – 8 February 1946) was a German chemist notable for re-synthesising diamorphine (independently from C.R. Alder Wright who synthesized it 23 years earlier), which was popularized under the Bayer trade name of "heroin".
Aspirin – Indigenous Americans have been using willow tree bark for thousands of years to reduce fever and pain as were the peoples of Assyria, Sumer, Ancient Egypt and Ancient Greece. When chemists analyzed willows in the last century, they discovered salicylic acid; the basis of the modern drug aspirin. [6]
Bayer contends that aspirin was discovered by Felix Hoffmann to help his father, who had arthritis. [29] Various sources support the conflicting claims. [30] [31] Most mainstream historians attribute the invention of aspirin to Hoffmann and/or Eichengrün. [25] [31]