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  2. Genetics of Down syndrome - Wikipedia

    en.wikipedia.org/wiki/Genetics_of_Down_syndrome

    Trisomy 21 is the cause of approximately 95% of observed Down syndrome, with 88% coming from nondisjunction in the maternal gamete and 8% coming from nondisjunction in the paternal gamete. [4] Mitotic nondisjunction after conception would lead to mosaicism, and is discussed later. Some cases have been reported of people with Down syndrome ...

  3. Down syndrome - Wikipedia

    en.wikipedia.org/wiki/Down_syndrome

    Down syndrome or Down's syndrome, [12] also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. [3] It is usually associated with developmental delays, mild to moderate intellectual disability , and characteristic physical features.

  4. Chromosome 21 - Wikipedia

    en.wikipedia.org/wiki/Chromosome_21

    Chromosome 21 is both the smallest human autosome and chromosome, [4] with 46.7 million base pairs (the building material of DNA) representing about 1.5 percent of the total DNA in cells. Most people have two copies of chromosome 21, while those with three copies of chromosome 21 (trisomy 21) have Down syndrome.

  5. Palpebral fissure - Wikipedia

    en.wikipedia.org/wiki/Palpebral_fissure

    The chromosomal conditions trisomy 9 and trisomy 21 (Down syndrome) can cause the palpebral fissures to be upslanted, [2] whereas Marfan syndrome can cause a downslant. [3] An increase in vertical height can be seen in genetic disorders such as cri-du-chat syndrome.

  6. Trisomy - Wikipedia

    en.wikipedia.org/wiki/Trisomy

    Karyotype of a human with Trisomy 21 (Down syndrome). Trisomies can occur with any chromosome, but often result in miscarriage rather than live birth.For example, Trisomy 16 is most common in human pregnancies, occurring in more than 1%, but the only surviving embryos are those having some normal cells in addition to the trisomic cells (mosaic trisomy 16). [3]

  7. MLB player Jake Burger: Why I picked No. 21 to honor my ... - AOL

    www.aol.com/mlb-player-jake-burger-why-045752848...

    As part of that opportunity for awareness, Jake chose the jersey No. 21 in honor of Trisomy 21, announcing the new number in collaboration with the Texas Rangers on Instagram on Jan. 17.

  8. List of people with Down syndrome - Wikipedia

    en.wikipedia.org/wiki/List_of_people_with_Down...

    The average IQ of a young adult with Down syndrome is 50, equivalent to the mental age of an 8- or 9-year-old child, but this number varies widely. [3] At the same time, they enjoy a rich social and emotional awareness. [4] Down syndrome is the most common chromosome abnormality in humans, [3] occurring in about one per 1000 babies born each ...

  9. Mattel launches first Barbie with Down syndrome to 'counter ...

    www.aol.com/news/mattel-launches-first-barbie...

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