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Significant side effects occur in about 25% of people. [6] Commonly these include loss of appetite, nausea, headache, and rash. [5] Severe side effects include bone marrow suppression, liver problems, Stevens–Johnson syndrome, and kidney problems. [6] [7] [4] It should not be used in people allergic to aspirin or sulfonamide. [6]
In the end, the drug led to significant weight loss across weekly dosages of 5, 10, and 15 milligrams, with a higher dose showing more benefits.
Thyroid hormones, another early weight loss drug, also raised energy expenditure but ceased to be used for weight loss due to cardiac risks and other adverse effects. [18] Selective thyromimetics that work on the thyroid hormone receptor beta may be able to exert some of the beneficial thermogenic effects of thyroid hormones with fewer adverse ...
Participants lost weight during the first 65 weeks of treatment and then maintained weight loss over the rest of the experiment. The four-year trial didn’t show any new safety concerns ...
Victoza. There are more semaglutide alternatives for weight loss. Victoza is also a GLP-1 receptor agonist, but the active ingredient is liraglutide. Liraglutide works in a similar way to ...
[84] [85] Preoperative weight loss can reduce operative time and hospital stay. [84] [86] [87] although there is insufficient evidence whether preoperative weight loss may be beneficial to reduce long-term morbidity or complications. [87] [88] Weight loss and decreases in liver size may be independent from the amount of calorie restriction. [85]
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