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Positive feedback is used in digital electronics to force voltages away from intermediate voltages into '0' and '1' states. On the other hand, thermal runaway is a type of positive feedback that can destroy semiconductor junctions. Positive feedback in chemical reactions can increase the rate of reactions, and in some cases can lead to explosions.
Positive feedback loops play a role by switching cells from low to high Cdk-activity. The interaction between the two types of loops is evident in mitosis. While positive feedback initiates mitosis, a negative feedback loop promotes the inactivation of the cyclin-dependent kinases by the anaphase-promoting complex.
The positive feedback of the rising phase slows and comes to a halt as the sodium ion channels become maximally open. At the peak of the action potential, the sodium permeability is maximized and the membrane voltage V m is nearly equal to the sodium equilibrium voltage E Na .
The pore of sodium channels contains a selectivity filter made of negatively charged amino acid residues, which attract the positive Na + ion and keep out negatively charged ions such as chloride. The cations flow into a more constricted part of the pore that is 0.3 by 0.5 nm wide, which is just large enough to allow a single Na + ion with a ...
The Hodgkin cycle represents a positive feedback loop in which an initial membrane depolarization leads to uncontrolled deflection of the membrane potential to near V Na. The initial depolarization must reach or surpass a certain threshold in order to activate voltage-gated Na + channels .
Positive feedback by estrogens also occurs in the gonadal axis of female mammals and is responsible for the midcycle surge of LH that stimulates ovulation. Although estrogens inhibit kisspeptin (Kp) release from kiss1 neurons in the ARC, estrogens stimulate Kp release from the Kp neurons in the AVPV.
Positive feedback occurs when the fed-back signal is in phase with the input signal. Under certain gain conditions, positive feedback reinforces the input signal to the point where the output of the device oscillates between its maximum and minimum possible states. Positive feedback may also introduce hysteresis into a circuit. This can cause ...
Some positive feedback from the output to one input of a comparator can increase the natural hysteresis (a function of its gain) it exhibits. Hysteresis is essential to the workings of some memristors (circuit components which "remember" changes in the current passing through them by changing their resistance).