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For example, the US National Institutes of Health program for Alzheimer's research, the National Plan to Address Alzheimer’s Disease, has a budget of US$3.98 billion for fiscal year 2026. [31] In the European Union , the 2020 Horizon Europe research programme awarded over €570 million for dementia-related projects.
Additionally, depending on the etiology of early onset dementia, family history may be a significant risk factor, especially for Alzheimer's early onset dementia. [8] Additionally it is more common for women to be diagnosed with Alzheimer's disease compared to men, for men it is more common to conduct vascular dementia.
[279] [280] Less than 1% of those with Alzheimer's have gene mutations that cause a much earlier development of the disease, around the age of 45, known as early-onset Alzheimer's disease. [281] More than 95% of people with Alzheimer's disease have the sporadic form (late onset, 80–90 years of age). [ 281 ]
Alzheimer’s usually is a disease of people over age 65 and while simply getting older is the main risk, the APOE gene has long been known to play some role. It comes in three main varieties.
In a 2006 survey of patients with long-term care insurance, the direct and indirect costs of caring for an Alzheimer's disease patient averaged $77,500 per year in the United States. [3] Caregivers themselves are subject to an increased incidence of depression, anxiety, and, in some cases, physical health issues.
Studies have shown that Alzheimer's disease (AD) patients are at an increased risk of morbidity and mortality from SARS-CoV-2, the virus that causes COVID-19. [1] AD is the most common cause of dementia worldwide and is clinically defined by amyloid beta plaques, neurofibrillary tangles , and activation of the brain's immune system .