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Countercurrent exchange is a key concept in chemical engineering thermodynamics and manufacturing processes, for example in extracting sucrose from sugar beet roots. Countercurrent multiplication is a similar but different concept where liquid moves in a loop followed by a long length of movement in opposite directions with an intermediate zone.
A countercurrent exchange system is utilized between the venous and arterial capillaries. Lowering the pH levels in the venous capillaries causes oxygen to unbind from blood hemoglobin because of the Root effect. This causes an increase in venous blood oxygen partial pressure, allowing the oxygen to diffuse through the capillary membrane and ...
A comparison between the operations and effects of a cocurrent and a countercurrent flow exchange system is depicted by the upper and lower diagrams respectively. In both it is assumed (and indicated) that red has a higher value (e.g. of temperature) than blue and that the property being transported in the channels therefore flows from red to blue.
The second application example for the MCSGP prototype is the separation of three MAb variants using a preparative weak cation-exchange resin. Although the intermediately eluting MAb variant can only be obtained with 80% purity at recoveries close to zero in a batch chromatographic process, the MCSGP process can provide 90% purity at 93% yield.
English: The exchange of heat in this diagram (1) is an example of countercurrent exchange. In this example the cold water requires the birds circulatory system to recycle heat and minimize heat loss through the skin. The warm arterial blood (2) flowing away from the heart warms up the cooler venous blood (3) heading towards the heart.
Countercurrent distribution, therefore, is a method of using a series of vessels (separatory funnels) to separate compounds by a sequence of liquid-liquid extraction operations. Contrary to liquid-liquid extraction, in the CCD instruments the upper phase is decanted from the lower phase once the phases have settled.
The high pressure gas is then cooled by immersing the gas in a cooler environment; the gas loses some of its energy (heat). Linde's patent example gives an example of brine at 10°C. The high pressure gas is further cooled with a countercurrent heat exchanger; the cooler gas leaving the last stage cools the gas going to the last stage.
Countercurrent exchange Countercurrent exchange is a mechanism used to transfer some property of a fluid from one flowing current of fluid to another across a semipermeable membrane, conductive material, or free surface (e.g. a liquid–gas absorption or extraction). Cryogenic liquefaction