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2. Melatonin as a medication and supplement - Wikipedia

   en.wikipedia.org/wiki/Melatonin_as_a_medication...

   Melatonin may be useful in the treatment of delayed sleep phase syndrome. [9] Melatonin is known to reduce jet lag, especially in eastward travel. However, if it is not taken at the correct time, it can instead delay adaptation. [30] Melatonin appears to have limited use against the sleep problems of people who work shift work. [31]

3. Experts Warn Against Viral "Sleepmaxxing" Trend - AOL

   www.aol.com/experts-warn-against-viral-sleepmax...

   Here's a scenario of what "sleepmaxxing" could look like: covering yourself in a weighted blanket and using mouth tape after taking melatonin as a white noise machine is on in the background and a ...

4. Ramelteon - Wikipedia

   en.wikipedia.org/wiki/Ramelteon

   Ramelteon, sold under the brand name Rozerem among others, is a melatonin agonist medication which is used in the treatment of insomnia. [3] [5] It is indicated specifically for the treatment of insomnia characterized by difficulties with sleep onset. [3] It reduces the time taken to fall asleep, but the degree of clinical benefit is small. [6]

5. Melatonin - Wikipedia

   en.wikipedia.org/wiki/Melatonin

   Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.

6. Somnifacient - Wikipedia

   en.wikipedia.org/wiki/Somnifacient

   Melatonin is an endogenous hormone synthesized in the pineal gland in the brain involved in promoting sleep. [30] It activates both melatonin receptors MT1 and MT2 to produce beneficial effects on sleep, therefore being used exogenously for mild insomnia. [31]

7. Delayed sleep phase disorder - Wikipedia

   en.wikipedia.org/wiki/Delayed_sleep_phase_disorder

   Large doses of melatonin can even be counterproductive: Lewy et al. [48] provide support to "the idea that too much melatonin may spill over onto the wrong zone of the melatonin phase-response curve." The long-term effects of melatonin administration have not been examined. In some countries, the hormone is available only by prescription or not ...