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  2. Noonan syndrome - Wikipedia

    en.wikipedia.org/wiki/Noonan_syndrome

    1.9 Neurological and cognitive ... Treatment: Based on the symptoms ... Noonan syndrome (NS) is a genetic disorder that may present with mildly unusual facial ...

  3. Noonan syndrome with multiple lentigines - Wikipedia

    en.wikipedia.org/wiki/Noonan_syndrome_with...

    Noonan syndrome with multiple lentigines (NSML) which is part of a group called Ras/MAPK pathway syndromes, [2] is a rare autosomal dominant, [3] multisystem disease caused by a mutation in the protein tyrosine phosphatase, non-receptor type 11 gene . The disease is a complex of features, mostly involving the skin, skeletal and cardiovascular ...

  4. RASopathy - Wikipedia

    en.wikipedia.org/wiki/RASopathy

    Legius syndrome, also known as NF1-like syndrome; Noonan syndrome with multiple lentigines (NSML), formerly called LEOPARD syndrome; SYNGAP1-related intellectual disability; Somatic mutations in the Ras/MAPK pathway can cause cancers and disorders such as RAS-associated autoimmune leukoproliferative disorder (RALD) or juvenile myelomonocytic ...

  5. Multiple complex developmental disorder - Wikipedia

    en.wikipedia.org/wiki/Multiple_complex...

    Multiple complex developmental disorder is likely to be caused by a number of different various genetic factors. Each individual with MCDD is unique from one another and displays different symptoms. Various neuropsychological disorders can also be found in family members of people with MCDD.

  6. Celine Dion Diagnosed With Rare Neurological Disease Called ...

    www.aol.com/entertainment/celine-dion-diagnosed...

    Celine Dion is sharing some personal news with her fans. In an emotional video posted to Instagram on Thursday, the 54-year-old entertainer reveals that she is battling Stiff Person Syndrome, a ...

  7. Jacqueline Noonan - Wikipedia

    en.wikipedia.org/wiki/Jacqueline_Noonan

    Jacqueline Anne Noonan (October 28, 1928 – July 23, 2020) was an American pediatric cardiologist best known for her characterization of a genetic disorder now called Noonan syndrome. [ 1 ] [ 2 ] She was also the original describer of hypoplastic left heart syndrome .

  8. Phakomatosis - Wikipedia

    en.wikipedia.org/wiki/Phakomatosis

    Many require lifelong surveillance and various treatments depending on the particular syndrome and presentation. Phakomatoses , also known as neurocutaneous syndromes , are a group of multisystemic diseases that most prominently affect structures primarily derived from the ectoderm such as the central nervous system, skin and eyes.

  9. Hemimegalencephaly - Wikipedia

    en.wikipedia.org/wiki/Hemimegalencephaly

    Hemimegalencephaly (HME), or unilateral megalencephaly, is a rare congenital disorder affecting all or a part of a cerebral hemisphere. [2] It causes severe seizures, which are often frequent and hard to control. A minority might have seizure control with medicines, but most will need removal or disconnection of the affected hemisphere as the ...