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Vitamin B 12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [2] It is one of eight B vitamins.It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [3]
Serum vitamin B 12 is a medical laboratory test that measure vitamin B 12 only in the blood binding to both transcobalamins. [1] Most of the time, 80–94% of vitamin B 12 in the blood binds to haptocorrin, while only 6–20% is binds to transcobalamin ll. [2] Only transcobalamin ll is "active" and can be used by the body. [1]
Hydroxocobalamin, or another form of vitamin B 12, are required for the body to make DNA. [7] Hydroxocobalamin was first isolated in 1949. [9] It is on the World Health Organization's List of Essential Medicines. [10] Hydroxocobalamin is available as a generic medication. [2] Commercially it is made using one of a number of types of bacteria. [11]
B12 is found in a wide array of animal-based foods, as it's produced by a gut bacteria that is then accumulated in the muscle tissue of most herbivorous animals, including fish, cows, chickens ...
One of the superpowers of vitamin B12 is that it is the only water-soluble vitamin that can be stored in the human body, Kitchens points out, and it can remain stored in the liver for several years.
But if you’re vegan or vegetarian or have a medical condition like pernicious anemia (when your body doesn’t have enough B12 to produce the amount of red blood cells it needs), vitamin B12 ...
Adenosylcobalamin (AdoCbl), also known as coenzyme B 12, cobamamide, and dibencozide, is one of the biologically active forms of vitamin B 12. [1] Schematic diagram of the propionate metabolic pathway.
“The combination of body and cognitive changes is a major clue that a treatable cause such as B12 deficiency could be the issue,” he says. How vitamin B12 deficiency is detected