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Vitamin B 12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [2] It is one of eight B vitamins.It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [3]
Serum vitamin B 12 is a medical laboratory test that measure vitamin B 12 only in the blood binding to both transcobalamins. [1] Most of the time, 80–94% of vitamin B 12 in the blood binds to haptocorrin, while only 6–20% is binds to transcobalamin ll. [2] Only transcobalamin ll is "active" and can be used by the body. [1]
Vitamin B 12 cannot be produced by the human body, and must be obtained from the diet. [2] The body normally gets enough vitamin B 12 from the consumption of foods from animal sources. [2] Inadequate dietary intake of animal products such as eggs, meat, milk, fish, fowl (and some type of edible algae) can result in a deficiency state. [134]
“Vitamin B12 is an essential water-soluble vitamin that plays a critical role in helping the brain and nervous system function,” says Ashley Kitchens, RDN, of Plant Centered Nutrition. “It ...
Vitamin B12 deficiency causes symptoms like fatigue, poor memory, a swollen tongue, and canker sores. How to recognize the signs and symptoms of vitamin B12 deficiency and properly treat it Skip ...
B12 is found in a wide array of animal-based foods, as it's produced by a gut bacteria that is then accumulated in the muscle tissue of most herbivorous animals, including fish, cows, chickens ...
Adenosylcobalamin (AdoCbl), also known as coenzyme B 12, cobamamide, and dibencozide, is one of the biologically active forms of vitamin B 12. [1] Schematic diagram of the propionate metabolic pathway.
While lower levels of vitamin B12 are associated with higher BMI and body fat, taking vitamin B12 supplements didn’t change body composition over the long term. More research is needed on the ...