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Vitamin B 12 deficiency can be determined, but not always. [14] This means it measures forms of vitamin B 12 that are "active" and can be used by the body, as well as the "inactive" forms, which cannot. [150] Vitamin B 12 deficiency can be found within normal levels, so clinical symptoms should be taken into account when a diagnosis is made. [2]
Other symptoms of vitamin B12 deficiency include memory loss, fatigue and weakness, nerve damage causing numbness and tingling in the arms and legs, dementia, depression, and seizures.
B12 is crucial for many important functions, and, with a few exceptions, the only way to get it is through animal-based foods or B12 supplements. “Vitamin B12 is an essential water-soluble ...
Neuropsychiatric symptoms can precede hematological signs and are often the presenting manifestation of the disease. [55] Vitamin B 12 serum levels are used to detect its deficiency, but do not distinguish its causes. Vitamin B 12 levels can be falsely high or low and data for sensitivity and specificity vary widely.
[6] [15] [26] Vitamin B 12 deficiency can also cause symptoms of mania and psychosis. [27] [28] Among other problems, weakened immunity, reduced fertility and interruption of blood circulation in women may occur. [29] The main type of vitamin B12 deficiency anemia is pernicious anemia, [30] characterized by a triad of symptoms:
Vitamin B12 deficiency symptoms. In addition to weakness and fatigue, a B12 deficiency may also prompt a slew of other symptoms, depending on the severity, including: pale skin.