Search results
Results From The WOW.Com Content Network
Corticotropin-releasing hormone (CRH) (also known as corticotropin-releasing factor (CRF) or corticoliberin; corticotropin may also be spelled corticotrophin) is a peptide hormone involved in stress responses. It is a releasing hormone that belongs to corticotropin-releasing factor family. In humans, it is encoded by the CRH gene. [5]
Corticotropes produce and release ACTH, a 39 amino acid peptide hormone, in response to corticotropic releasing hormone (CRH) release from the hypothalamus. CRH is a 41-amino-acid peptide hormone that is secreted by the parvocellular neurosecretory cells, which are found within the paraventricular nucleus of the hypothalamus. [9]
The paraventricular nucleus transports CRH to the anterior pituitary, stimulating adrenocorticotropic hormone (ACTH) release via CRH type 1 receptors, thereby activating the hypothalamic-pituitary-adrenal axis (HPA) and, thus, glucocorticoid release. CRH is evolutionary-related to a number of other active peptides. Urocortin acts in vitro to ...
ACTH is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of cortisol and androgens by the zona fasiculata and zona reticularis ...
Corticotropin-releasing hormone receptors (CRHRs), also known as corticotropin-releasing factor receptors (CRFRs) are a G protein-coupled receptor family that binds corticotropin-releasing hormone (CRH). [1] There are two receptors in the family, designated as type 1 and 2, each encoded by a separate gene (CRHR1 and CRHR2 respectively).
Corticotropin-releasing hormone receptor 1 (CRHR1) is a protein, also known as CRF 1, with the latter (CRF 1) now being the IUPHAR-recommended name. [4] In humans, CRF 1 is encoded by the CRHR1 gene at region 17q21.31, beside micrototubule-associated protein tau MAPT .
Releasing hormones and inhibiting hormones are hormones whose main purpose is to control the release of other hormones, either by stimulating or inhibiting their release. They are also called liberins ( / ˈ l ɪ b ə r ɪ n z / ) and statins ( / ˈ s t æ t ɪ n z / ) (respectively), or releasing factors and inhibiting factors .
5-DHT or DHT is a male reproductive hormone that targets the prostate gland, bulbourethral gland, seminal vesicles, penis and scrotum and promotes growth/mitosis/cell maturation and differentiation. Testosterone is converted to 5-DHT by 5alpha-reductase, usually with in the target tissues of 5-DHT because of the need for high concentrations of ...