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Idoxuridine is an anti-herpesvirus antiviral drug.. It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing.
Ganciclovir (Cytovene) [9] Cytomegalovirus (CMV) [10] Competitive nucleoside analogue dGTP inhibitor 1988 Ibacitabine: Herpes labialis: Ibalizumab (Trogarzo) [11] HIV Entry inhibitor 2018 Idoxuridine: Herpes: dU analogue inhibitor 1962 Imiquimod: Genital wart, Basal cell carcinoma, Actinic keratosis: Opioid growth factor receptor (OGFr) agonist ...
Cidofovir is only available as an intravenous formulation. Cidofovir is to be administered with probenecid which decreases side effects to the kidney. [22] Probenecid mitigates nephrotoxicity by inhibiting organic anion transport of the proximal tubule epithelial cells of the kidney. [23]
The antiviral drug aciclovir (bottom), a nucleoside analogue that functions by mimicking guanosine (top). Nucleoside analogues are structural analogues of a nucleoside, which normally contain a nucleobase and a sugar.
Trifluridine (also called trifluorothymidine; abbreviation TFT or FTD [1]) is an anti-herpesvirus antiviral drug, used primarily as prescription eyedrops. It was sold under the trade name Viroptic by Glaxo Wellcome, now merged into GlaxoSmithKline .
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That day, in August 2013, Patrick got in the car and put the duffel bag on a seat. Inside was a talisman he’d been given by the treatment facility: a hardcover fourth edition of the Alcoholics Anonymous bible known as “The Big Book.”