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  2. Proton-pump inhibitor - Wikipedia

    en.wikipedia.org/wiki/Proton-pump_inhibitor

    Proton-pump inhibitors ... In infants, acid suppression therapy is frequently prescribed to treat symptomatic gastroesophageal reflux in otherwise healthy infants ...

  3. Drugs for acid-related disorders - Wikipedia

    en.wikipedia.org/wiki/Drugs_for_acid-related...

    The H 2 receptor antagonists are a class of drugs used to block the action of histamine on parietal cells in the stomach, decreasing the production of acid by these cells. H 2 antagonists are used in the treatment of dyspepsia, although they have been surpassed in popularity by the more effective [1] proton pump inhibitors.

  4. Pantoprazole - Wikipedia

    en.wikipedia.org/wiki/Pantoprazole

    Pantoprazole is a proton pump inhibitor that decreases gastric acid secretion. [5] It works by inactivating (H+/K+)-ATPase function in the stomach. [9] [5] The study of pantoprazole began in 1985, and it came into medical use in Germany in 1994. [10] It is available as a generic medication.

  5. Dexlansoprazole - Wikipedia

    en.wikipedia.org/wiki/Dexlansoprazole

    Effectiveness is similar to other proton pump inhibitors (PPIs). [4] It is taken by mouth. [3] Common side effects include diarrhea, abdominal pain, and nausea. [3] Serious side effects may include osteoporosis, low blood magnesium, Clostridioides difficile infection, anaphylaxis, and pneumonia. [3] Use in pregnancy and breastfeeding is of ...

  6. Rabeprazole - Wikipedia

    en.wikipedia.org/wiki/Rabeprazole

    Rabeprazole, like other proton pump inhibitors such as omeprazole, is used for the purposes of gastric acid suppression. [11] This effect is beneficial for the treatment and prevention of conditions in which gastric acid directly worsens symptoms, such as duodenal and gastric ulcers. [11]

  7. Discovery and development of proton pump inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Proton pump inhibitors (PPIs) block the gastric hydrogen potassium ATPase (H + /K + ATPase) and inhibit gastric acid secretion. These drugs have emerged as the treatment of choice for acid-related diseases, including gastroesophageal reflux disease (GERD) and peptic ulcer disease. PPIs also can bind to other types of proton pumps such as those ...