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OSU-03012 (AR-12) is a celecoxib derivative with anticancer and anti-microbial activity. Unlike celecoxib, OSU-03012 does not inhibit COX, but inhibits several other important enzymes instead which may be useful in the treatment of some forms of cancer, [1] [2] When combined with PDE5 inhibitors such as sildenafil or tadalafil, OSU-03012 was found to show enhanced anti-tumour effects in cell ...
Ismaili communities in Afghanistan are less populous than the Twelver who consider the Ismaili heretical. They are found primarily in and near the eastern Hazarajat, in the Baghlan area north of the Hindu Kush, among the mountain Tajik of Badakhshan, and amongst the Wakhi in the Wakhan Corridor. The Ismailis believe that the series of Imamat or ...
Israel's Channel 2 was operated by the Second Authority for Television and Radio, but was programmed by two rotating companies, Keshet Media Group and Reshet.As part of a larger series of reforms to Israel's broadcast system to increase diversity and competition, Channel 2 was shut down, and both concessionaires were granted their own, standalone channels; Keshet 12 officially launched on 1 ...
Surayya, a village near Madinah, Hijaz [31] 8 42 34 Strengthened the network of deputies in the Shia community. He sent them instructions, and received in turn financial contributions of the faithful from the khums and religious vows. [31] He was poisoned in Samarra, Iraq on the order of Caliph Al-Mu'tazz. [32]
The zakat rates historically differed depending on the asset type: 2.5% of animals, 5% of minerals, and 10% of crops. Among Khoja Ismailis, the zakat is 12.5% of cash income and among other Ismailis of Iran, Syria, Central Asia, and China, the zakat is 10% of cash income and other %s of non-cash assets like crops and livestock. [citation needed]
The 12th Army was reconstituted on the Western Front near the Elbe River on April 10, 1945. [4] With the command staff of the dissolved Army Group North, the army consisted of XLVIII, XX, and XXXI Army Corps. [2] Under General Walther Wenck, the 12th Army made the last attempt by a German Army to relieve the besieged capital during the Battle ...
In July 2018, she gave birth to her first child, a boy named Hudson. [12] In 2021, [ 13 ] Waissel won a scholarship and completed the postgraduate law course at BPP University . In January 2023, it was reported that she was trying to sue Syco Entertainment for breach of duty of care , and had founded the OWHL Foundation, a charity "overseeing ...
Stephen Wise Temple is a large Reform Jewish congregation in the Bel Air neighborhood of Los Angeles, California, in the United States. Founded in 1964 by the late Rabbi Isaiah Zeldin , with 35 families, the congregation grew rapidly.