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Dactinomycin, also known as actinomycin D, is a chemotherapy medication used to treat a number of types of cancer. [2] This includes Wilms tumor, rhabdomyosarcoma, Ewing's sarcoma, trophoblastic neoplasm, testicular cancer, and certain types of ovarian cancer. [2]
Actinomyces species may form endospores, and while individual bacteria are rod-shaped, Actinomyces colonies form fungus-like branched networks of hyphae. [3] The aspect of these colonies initially led to the incorrect assumption that the organism was a fungus and to the name Actinomyces, "ray fungus" (from Greek actis, ray or beam, and mykes ...
Actinomycetales can be found mostly in soil and decaying organic matter, as well as in living organisms such as humans and animals. They form symbiotic nitrogen fixing associations with over 200 species of plants, and can also serve as growth promoting or biocontrol agents, or cause disease in some species of plants.
Actinomycetota, especially Streptomyces spp., are recognized as the producers of many bioactive metabolites that are useful to humans in medicine, such as antibacterials, [18] antifungals, [19] antivirals, antithrombotics, immunomodifiers, antitumor drugs, and enzyme inhibitors; and in agriculture, including insecticides, herbicides, fungicides ...
Actinomyces israelii is a species of Gram-positive, rod-shaped bacteria within the genus Actinomyces. Known to live commensally on and within humans, A. israelii is an opportunistic pathogen and a cause of actinomycosis .
Actinomycosis is a rare infectious bacterial disease caused by the gram-positive Actinomyces species. [1] The name refers to ray-like appearance of the organisms in the granules. About 70% of infections are due to either Actinomyces israelii or A. gerencseriae. [1] Infection can also be caused by Streptomyces somaliensis and Propionibacterium ...
The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) [3] and National Center for Biotechnology Information (NCBI). [ 1 ] Acidothermales Sen et al. 2014
Cutaneous actinomycosis is a chronic disease that affects the deep subcutaneous tissue of the skin. Caused by an anaerobic, Gram-positive, filamentous type of bacteria in the genus Actinomyces, [1]: 270 invasion of the soft tissue leads to the formation of abnormal channels leading to the skin surface (external sinus tracts) that discharge pale yellow sulfur granules.