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Inbreeding is also used to reveal deleterious recessive alleles, which can then be eliminated through assortative breeding or through culling. In plant breeding, inbred lines are used as stocks for the creation of hybrid lines to make use of the effects of heterosis. Inbreeding in plants also occurs naturally in the form of self-pollination.
Darwin's wife, Emma, was his first cousin, and he was concerned about the impact of inbreeding on his ten children, three of whom died at age ten or younger; three others had childless long-term marriages. [16] [17] [18] Humans do not seek to completely minimize inbreeding, but rather to maintain an optimal amount of inbreeding vs. outbreeding.
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Setzer said that although she acted quickly, giving her child a long bath, washing all her bedding and clothing and administering Benadryl, Emmalee was still sickened by the incident.
Genetic purging is the increased pressure of natural selection against deleterious alleles prompted by inbreeding. [1]Purging occurs because deleterious alleles tend to be recessive, which means that they only express all their harmful effects when they are present in the two copies of the individual (i.e., in homozygosis).
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Common physical symptoms show a short leg, the ankle and foot being short and deformed, absence of rays and bowing of the tibia. [4] Another physical symptom is the presence of contralateral oligosyndactyly of the hand. [1] Hecht Scott syndrome is also associated with psychosocial morbidity and mortality. [4]
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