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Feet of a baby born to a mother who had taken thalidomide while pregnant. In the late 1950s and early 1960s, the use of thalidomide in 46 countries was prescribed to women who were pregnant or who subsequently became pregnant, and consequently resulted in the "biggest anthropogenic medical disaster ever," with more than 10,000 children born with a range of severe deformities, such as ...
Thalidomide, sold under the brand names Contergan and Thalomid among others, is an oral medication used to treat a number of cancers (e.g., multiple myeloma), graft-versus-host disease, and many skin disorders (e.g., complications of leprosy such as skin lesions).
Primarily prescribed as a sedative or hypnotic, thalidomide also claimed to cure "anxiety, insomnia, gastritis, and tension". [8] Afterwards it was used against nausea and to alleviate morning sickness in pregnant women. Thalidomide became an over-the-counter drug in Germany around 1960, i.e. it could be bought without a prescription. Shortly ...
In the elderly there was a particularly high risk of strokes and other heart-related diseases. In children, Johnson & Johnson’s own data would ultimately count somnolence (51 percent of the time), headaches (29 percent), vomiting (20 percent) and bloating, nausea or other stomach ailments (15 percent), among other side effects.
Thalidomide, developed by the German firm Gruenenthal, killed an estimated 80,000 children around the world before they were born, and 20,000 more were born with defects.
Frances Kathleen Oldham Kelsey CM (née Oldham; July 24, 1914 – August 7, 2015) was a Canadian-American [1] pharmacologist and physician. As a reviewer for the U.S. Food and Drug Administration (FDA), she refused to authorize thalidomide for market because she had concerns about the lack of evidence regarding the drug's safety. [2]
On June 20, 2013, Plan B became available over the counter, helping women avoid point-of-sale barriers to emergency contraception. A lot has changed in reproductive care in the U.S. since then ...
Metformin is a medication in a class of compounds called biguanides, according to the U.S. National Library of Medicine. These medications reduce the amount of glucose the body absorbs from food ...