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Schaalia turicensis (formerly Actinomyces turicensis) is a Gram-positive bacterium found in the flora of the oral cavity, gut, skin, and female urogenital tract. [2] S. turicensis is an important human pathogen of soft tissue infections in the lower body. [3] S. turicensis is a facultative anaerobe, growing in air and CO 2 conditions.
Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria, with greater activity against both types of organism than third-generation agents. A 2007 meta-analysis suggested when data of trials were combined, mortality was increased in people treated with cefepime compared with other β-lactam antibiotics. [1]
Actinomyces is a genus of the Actinomycetia class of bacteria. They all are Gram-positive and facultatively anaerobic , growing best under anaerobic conditions. [ 2 ] Actinomyces species may form endospores , and while individual bacteria are rod-shaped , Actinomyces colonies form fungus -like branched networks of hyphae . [ 3 ]
Actinomycosis is most frequently caused by A. israelii. [4] It is a normal colonizer of the vagina, [ 5 ] colon, and mouth. [ 6 ] Infection is established first by a breach of the mucosal barrier during various procedures (dental, gastrointestinal), aspiration, or pathologies such as diverticulitis . [ 7 ]
Cefepime/enmetazobactam, sold under the brand name Exblifep, is a medication used for the treatment of urinary tract infections. [ 1 ] [ 2 ] It is a fixed dose combination containing cefepime , a cephalosporin antibacterial; and enmetazobactam , a beta-lactamase inhibitor .
Actinomyces and its associated species have, for a long time, been implicated in human infections, particularly those of the mouth, pharynx, distal esophagus, and genitourinary tract. [9] Within the last 10 years, A. massiliensis has been detected in blood, and most Actinomyces bacteremias stem from oral sources. [9]
Actinomycetoma is a chronic bacterial subcutaneous infection caused by Actinomyces that affect the skin and connective tissue. [1] It is, therefore, a form of actinomycosis . [ 2 ] Mycetoma is a broad term which includes actinomycetoma and eumycetoma under it.
Pathogen reduction using riboflavin and UV light is a method by which infectious pathogens in blood for transfusion are inactivated by adding riboflavin and irradiating with UV light. [ 1 ] [ 2 ] [ 3 ] This method reduces the infectious levels of disease-causing agents that may be found in donated blood components, while still maintaining good ...