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Eszopiclone, sold under the brand name Lunesta among others, is a medication used in the treatment of insomnia. [3] [4] Evidence supports slight to moderate benefit up to six months. [5] [4] [6] It is taken by mouth. [3] [5] Common side effects include headache, dry mouth, nausea, and dizziness. [5]
Intrathecal baclofen is used for severe spasticity of spinal cord origin, that is refractive to maximum doses of oral antispasmodic agents, or who experience intolerable side effects. [21] [22] Baclofen may be used off-label as a treatment for alcohol use disorder to reduce the risk of relapse, and to increase the number of days that a person ...
Lunesta (eszopiclone) – a non-benzodiazepine hypnotic; Luvox (fluvoxamine) – an antidepressant of the SSRI class; Loxitane – an antipsychotic used in the treatment of mood disorders and schizophrenia; Lyrica – treats nerve and muscle pain, including fibromyalgia. It can also treat seizures.
The best-known cyclopyrrolone derivatives are zopiclone (Imovane) and its active single-enantiomer component, eszopiclone (Lunesta), which are used to treat insomnia, and have a known potential for abuse. Other cyclopyrrolones include: Pagoclone – anxiolytic; Pazinaclone – anxiolytic; Suproclone – anxiolytic
Side effects of lemborexant include somnolence, fatigue, headache, and abnormal dreams. [3] [8] The medication is a dual orexin receptor antagonist (DORA). [3] [8] It acts as a selective dual antagonist of the orexin receptors OX 1 and OX 2. [3] [8] Lemborexant has a long elimination half-life of 17 to 55 hours and a time to peak of about 1 to ...
From or to a drug trade name: This is a redirect from (or to) the trade name of a drug to (or from) the international nonproprietary name (INN).
The ultrashort 1hr half-life gives Zaleplon a unique advantage over other hypnotics because of its lack of next-day residual effects on driving and other performance-related skills. [ 35 ] [ 36 ] Zaleplon is primarily metabolised by aldehyde oxidase into 5-oxozaleplon, and its half-life may be affected by substances which inhibit or induce ...
A baclofen pump has been used to treat patients of all ages exhibiting muscle spasticity along with dystonia. The pump delivers baclofen via a catheter to the thecal space surrounding the spinal cord. The pump itself is placed in the abdomen. It can be refilled periodically by access through the skin. Baclofen can also be taken in tablet form [40]
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