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  2. Management of schizophrenia - Wikipedia

    en.wikipedia.org/wiki/Management_of_schizophrenia

    A new first-in-class antipsychotic that targets multiple neurotransmitter systems called lumateperone (ITI-007), was trialed and approved by the FDA in December 2019 for the treatment of schizophrenia in adults. [24] [26] [27] Lumateperone is a small molecule agent that shows improved safety, and tolerance.

  3. Antipsychotic - Wikipedia

    en.wikipedia.org/wiki/Antipsychotic

    Antipsychotic drug treatment is a key component of schizophrenia treatment recommendations by the National Institute of Health and Care Excellence (NICE), [23] the American Psychiatric Association, [24] and the British Society for Psychopharmacology. [25]

  4. Typical antipsychotic - Wikipedia

    en.wikipedia.org/wiki/Typical_antipsychotic

    Typical antipsychotics (also known as major tranquilizers, and first generation antipsychotics) are a class of antipsychotic drugs first developed in the 1950s and used to treat psychosis (in particular, schizophrenia). Typical antipsychotics may also be used for the treatment of acute mania, agitation, and other conditions.

  5. FDA approves 1st new drug for schizophrenia in more ... - AOL

    www.aol.com/fda-approves-1st-drug-schizophrenia...

    The U.S. Food and Drug Administration (FDA) on Thursday approved the first new drug to treat people with schizophrenia in more than 30 years. Cobenfy, manufactured by Bristol Myers Squibb ...

  6. Treatment of mental disorders - Wikipedia

    en.wikipedia.org/wiki/Treatment_of_mental_disorders

    Aripiprazole was the first drug approved by the US Food and Drug Administration for adjunctive treatment of MDD in adults with inadequate response to antidepressant therapy in the current episode. Recommended doses of aripiprazole range from 2 mg/d to 15 mg/d based on 2 large, multicenter randomized, double-blind, placebo-controlled studies ...

  7. Dopamine antagonist - Wikipedia

    en.wikipedia.org/wiki/Dopamine_antagonist

    Dopamine receptor flow chart. Dopamine receptors are all G protein–coupled receptors, and are divided into two classes based on which G-protein they are coupled to. [1] The D 1-like class of dopamine receptors is coupled to Gα s/olf and stimulates adenylate cyclase production, whereas the D 2-like class is coupled to Gα i/o and thus inhibits adenylate cyclase production.

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