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Cystic fibrosis transmembrane conductance regulatory (CFTR) protein. Underrepresented populations, especially black and hispanic populations with cystic fibrosis are often not successfully diagnosed. [1] This is in part due to the minimal dissemination of existing data on patients from these underrepresented groups.
Racial and ethnic demographics of the United States in percentage of the population. The United States census enumerated Whites and Blacks since 1790, Asians and Native Americans since 1860 (though all Native Americans in the U.S. were not enumerated until 1890), "some other race" since 1950, and "two or more races" since 2000. [2]
Spirometers in the US utilize population-specific standards or correction factors of 10% to 15% for Black persons and 4% to 6% for Asian people. [122] Thus, equations derived from Black populations will yield a higher percentage of predicted lung function values than those derived from White populations, which may underestimate lung disease ...
The table below shows the percentage of free blacks as a percentage of the total black population in various U.S. regions and U.S. states between 1790 and 1860 (the blank areas on the chart below mean that there is no data for those specific regions or states in those specific years). [citation needed]
Cystic fibrosis (also known as CF or mucoviscidosis) is an autosomal recessive genetic disorder affecting most critically the lungs, and also the pancreas, liver, and intestine.
Cystic fibrosis is underdiagnosed in populations of African ancestry, because it is thought of as a 'White' disease." [26] Information about a person's population of origin may aid in diagnosis, and adverse drug responses may vary by group.
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The table also excludes all mixed raced/multiracial persons from the racial categories, assigning them to their own category. The information on Guam, the Northern Mariana Islands, and American Samoa, add up to more than 100% as the racial data for Hispanics was not broken out separately in the 2020 Census.