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Eisenmenger syndrome or Eisenmenger's syndrome is defined as the process in which a long-standing left-to-right cardiac shunt caused by a congenital heart defect (typically by a ventricular septal defect, atrial septal defect, or less commonly, patent ductus arteriosus) causes pulmonary hypertension [1] [2] and eventual reversal of the shunt into a cyanotic right-to-left shunt.
Since the 1950s, as the understanding of heart and lung disease has evolved, Eisenmenger's syndrome is the name given to the situation in which a cardiac defect causes too much blood flow to the lungs, which in turn causes changes to the blood vessels in the lungs (pulmonary hypertension) and a reversal of blood flow so that now there is ...
Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...
Many patients eventually require oxygen supplementation at home. In severe cases that are difficult to control, chronic treatment with oral corticosteroids may be necessary, although this is fraught with significant side effects. COPD is generally irreversible although lung function can partially recover if the patient stops smoking.
Less common signs/symptoms include non-productive cough and exercise-induced nausea and vomiting. [12] Coughing up of blood may occur in some patients, particularly those with specific subtypes of pulmonary hypertension such as heritable pulmonary arterial hypertension, Eisenmenger syndrome and chronic thromboembolic pulmonary hypertension. [16]
Andersen–Tawil syndrome: This condition affects the QT interval (in blue) Antley–Bixler syndrome: Barth syndrome: Brugada syndrome: Cantú syndrome: genetic (Chromosome 12, autosomal dominant) Cardiac syndrome X: Cardiorenal syndrome: Kidney Cat eye syndrome: CHARGE syndrome: Coffin–Lowry syndrome: genetic (RPS6KA3 gene mutation ...
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