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The mean corpuscular volume, or mean cell volume (MCV), is a measure of the average volume of a red blood corpuscle (or red blood cell). The measure is obtained by multiplying a volume of blood by the proportion of blood that is cellular (the hematocrit), and dividing that product by the number of erythrocytes (red blood cells) in that volume.
The normal mean corpuscular volume (abbreviated to MCV on full blood count results, and also known as mean cell volume) is approximately 80–100 fL. When the MCV is <80 fL, the red cells are described as microcytic and when >100 fL, macrocytic (the latter occurs in macrocytic anemia). The MCV is the average red blood cell size.
an uncompensated increase in plasma volume (e.g., pregnancy, fluid overload); a B2 deficiency [3] a B6 deficiency [3] or a mixture of conditions producing microcytic and macrocytic anemia. [1] Blood loss, suppressed production of RBCs or hemolysis represent most cases of normocytic anemia.
Pregnant women need almost twice as much iron as women who are not pregnant do. Not getting enough iron during pregnancy raises risk of premature birth or a low-birth-weight baby. [ 23 ] Hormonal changes in the pregnant woman result in an increase in circulating blood volume to 100 mL/kg with a total blood volume of approximately 6000–7000 mL.
Hemoglobin. The mean corpuscular hemoglobin concentration (MCHC) is a measure of the concentration of hemoglobin in a given volume of packed red blood cell.. It is calculated by dividing the hemoglobin by the hematocrit.
Hypochromic anemia may be caused by vitamin B6 deficiency from a low iron intake, diminished iron absorption, or excessive iron loss. It can also be caused by infections (e.g. hookworms) or other diseases (i.e. anemia of chronic disease), therapeutic drugs, copper toxicity, and lead poisoning.
Symptoms, Complete blood count, Peripheral blood smear, Vitamin B12 level, Red cell folate level Macrocytosis is a condition where red blood cells are larger than normal. [ 1 ] These enlarged cells, also known as macrocytes, are defined by a mean corpuscular volume (MCV) that exceeds the upper reference range established by the laboratory and ...
RDW-SD is calculated as the width (in fL) of the RBC size distribution histogram at the 20% height level. This parameter is, therefore, not influenced by the average RBC size (mean corpuscular volume, MCV). [7] RDW-CV (expressed in %) is calculated with the following formula: RDW-CV = (1 standard deviation of RBC volume ÷ MCV) × 100%. [8]