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An antianginal is a drug used in the treatment of angina pectoris, a symptom of ischaemic heart disease. Myocardial ischemia arises from the dysfunction of coronary macrovascular or microvascular components, leading to a compromised supply of oxygen and nutrients to the myocardium.
Common side effects include headache and low blood pressure. [1] The low blood pressure can be severe. [1] It is unclear if use in pregnancy is safe for the fetus. [1] It should not be used together with medications within the PDE5 inhibitor family such as sildenafil due to the risk of low blood pressure. [1]
The approved uses are for the long-term treatment of hypertension and angina pectoris.In hypertension, recent clinical guidelines generally favour diuretics and ACE inhibitors, although calcium channel antagonists, along with thiazide diuretics, are still favoured as primary treatment for patients over 55 and black patients.
Pfizer originally discovered the medication in 1989 while looking for a treatment for angina. [11] It was approved for medical use in the United States and in the European Union in 1998. [ 5 ] [ 8 ] [ 11 ] [ 12 ] In 2022, it was the 157th most commonly prescribed medication in the United States, with more than 3 million prescriptions.
Like other medications for the treatment of (ED), Cialis — and its generic version, tadalafil — can cause adverse effects at first. Fortunately, most tadalafil side effects are mild and ...
Ranolazine was approved by the FDA in January 2006, for the treatment of patients with chronic angina as a second-line treatment in addition to other drugs. [13] In 2007 the label was updated to make ranolazine a first-line treatment, alone or with other drugs. [13] In April 2008 ranolazine was approved by the European EMEA for use in angina. [25]
The supplements we just went over don’t have the same requirements as drugs approved by the FDA (U.S. Food and Drug Administration), like Fluoxetine (Prozac) or Sertraline (Zoloft).
Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain (), heart failure and esophageal spasms. [2] It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. [2]