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12-hydroxystearic acid is prepared by the hydrogenation of castor oil, followed by saponification with sodium hydroxide and acidification with hydrochloric acid. [3] This process converts ricinoleate moieties in castor oil triglycerides to 12-hydroxystearate, with stearate as a byproduct from dehydration of the hydroxy acid followed by ...
The Compendium of Pharmaceuticals and Specialties: The Canadian Drug Reference for Health Professionals, more commonly known by its abbreviation CPS, [1] is a reference book that contains drug monographs and numerous features which help healthcare professionals prescribe and use drugs safely and appropriately.
This listing is limited to those independent companies and subsidiaries notable enough to have their own articles in Wikipedia. Both going concerns and defunct firms are included, as well as firms that were part of the pharmaceutical industry at some time in their existence, provided they were engaged in the production of human (as opposed to veterinary) therapeutics.
CIPA members sell pharmaceuticals and maintenance medications to individuals upon receipt of a valid prescription. In addition to selling Health Canada approved medications from their licensed Canadian pharmacies, CIPA members also have relationships with regulated international pharmacies and inspected fulfillment centres that directly deliver ...
Founded in 1974 by Barry Sherman, the company is the largest producer of generic drugs in Canada, with annual sales exceeding CA$2.5 billion. [5] By 2023, Apotex employed close to 8,000 people as Canada's largest drug manufacturer, with over 300 products selling in over 115 countries.
Hydrogenation and saponification of castor oil yields 12-hydroxystearic acid, which is then reacted with lithium hydroxide or lithium carbonate to give high-performance lubricant grease. [ 46 ] Since it has a relatively high dielectric constant (4.7), highly refined and dried castor oil is sometimes used as a dielectric fluid within high ...