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Thiamine supplements are generally well tolerated. Allergic reactions, including anaphylaxis, may occur when repeated doses are given by injection. [7] [8] Thiamine is on the World Health Organization's List of Essential Medicines. [9] It is available as a generic medication, and in some countries as a non-prescription dietary supplement. [7]
Relatively common (hospitalized people) [2] Magnesium deficiency is an electrolyte disturbance in which there is a low level of magnesium in the body. [3] Symptoms include tremor, poor coordination, muscle spasms, loss of appetite, personality changes, and nystagmus. [1][2] Complications may include seizures or cardiac arrest such as from ...
Vitamin C megadosage is a term describing the consumption or injection of vitamin C (ascorbic acid) in doses well beyond the current United States Recommended Dietary Allowance of 90 milligrams per day, and often well beyond the tolerable upper intake level of 2,000 milligrams per day. [1] There is no strong scientific evidence that vitamin C ...
Benfotiamine. Benfotiamine (rINN, or S-benzoylthiamine O-monophosphate) is a synthetic, fat-soluble, S -acyl derivative of thiamine (vitamin B1) that is approved in some countries as a medication or dietary supplement to treat diabetic sensorimotor polyneuropathy. Benfotiamine was developed in late 1950s in Japan. [1][2]
Thiamine deficiency. Thiamine deficiency is a medical condition of low levels of thiamine (vitamin B 1). [1] A severe and chronic form is known as beriberi. [1][7] The name beriberi was possibly borrowed in the 18th century from the Sinhalese phrase බැරි බැරි (bæri bæri, “I cannot, I cannot”), owing to the weakness caused ...
Adverse effects found in clinical trials are usually limited to headache and gastrointestinal discomfort when high doses are used. While daily use can result in tolerance and paradoxical drowsiness, increasing the dose is strongly discouraged and side effects can include diarrhea, bladder infections, bronchitis, back pain, abdominal pain, insomnia, constipation, gastroenteritis, headache ...
Symptoms include weakness, confusion, decreased breathing rate, and decreased reflexes. Hypermagnesemia can greatly increase the chances of adverse cardiovascular events. [1][3] Complications may include low blood pressure and cardiac arrest. [1][5] It is typically caused by kidney failure or is treatment-induced such as from antacids or ...
When using a MAO inhibitor (MAOI), an intake of approximately 10 to 25 mg of tyramine is required for a severe reaction, compared to 6 to 10 mg for a mild reaction. [ 36 ] Tyramine, like phenethylamine , is a monoaminergic activity enhancer (MAE) of serotonin , norepinephrine , and dopamine in addition to its catecholamine-releasing activity.