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Dabigatran, sold under the brand name Pradaxa among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. [ 6 ] [ 7 ] Specifically it is used to prevent blood clots following hip or knee replacement and in those with a history of prior clots. [ 6 ]
Medical use. Direct factor Xa inhibitors include rivaroxaban, apixaban and edoxaban, and are types of direct oral anticoagulant (DOAC), which are blood thinning drugs, one of the classes of antithrombotic drugs. [4][5][6] They are commonly prescribed to treat and prevent blood clots in veins, prevent stroke and embolism in people with non ...
Idarucizumab is a non-competitive inhibitor that forms complexes with dabigatran to counteract its anticoagulant effect within minutes of administration. [8] It binds to dabigatran that is free or bound to thrombin, as well as dabigatran's active metabolites. [9] Idarucizumab is specific to dabigatran and has an affinity that is around 350 ...
Some of the most common reasons to change antidepressants include: Side effects. Many antidepressants can cause side effects, including nausea, digestive issues, headaches and difficulty sleeping ...
Dabigatran was the subject of 3,781 serious adverse events reported to the FDA in 2011. This included 542 patient deaths , 2.367 hemorrhages, 291 acute renal failures and 644 stroke. Warfarin was the subject of 1,106 serious adverse events, including 72 deaths.
Over on the male side, Dr. Primack says that obesity is often the cause of male breast growth. “Male breast growth is often caused by an imbalance of estrogen levels. This can result in physical ...
While your liver and stomach can usually rebound if you stop drinking, with inflammation comes an increased cancer risk over time. Alcohol can also impair your ability to get restorative rest ...
Long-term use of benzodiazepines can induce perceptual disturbances and depersonalization in some people, even in those taking a stable daily dosage, and it can also become a protracted withdrawal feature of the benzodiazepine withdrawal syndrome. [55] In addition, chronic use of benzodiazepines is a risk factor for blepharospasm. [56]