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Trimethoprim. Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. [1] Other uses include for middle ear infections and travelers' diarrhea. [1] With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS. [1][2] It is taken orally (swallowed by mouth).
Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
The effects of trimethoprim causes a backlog of dihydrofolate (DHF) and this backlog can work against the inhibitory effect the drug has on tetrahydrofolate biosynthesis. This is where the sulfamethoxazole comes in; its role is in depleting the excess DHF by preventing it from being synthesised in the first place.
Methaemoglobinaemia. Erythema multiforme. Low blood sugar. Hepatitis (liver swelling) Crystalluria (crystals in the urine) Urinary obstruction causing difficulty passing urine. Lowered mental acuity. Depression. Tremor.
A urinary tract infection (UTI) is an infection that affects a part of the urinary tract. [ 1 ] Lower urinary tract infections may involve the bladder (cystitis) or urethra (urethritis) while upper urinary tract infections affect the kidney (pyelonephritis). [ 10 ] Symptoms from a lower urinary tract infection include suprapubic pain, painful ...
Teeth discoloration and same side effects as tetracycline. Not to be given to children and pregnant or lactating women. Similar structure with tetracycline, but five times stronger, big volume distribution and long half-time in the body Tinidazole: Tindamax Fasigyn: Protozoal infections: Upset stomach, bitter taste, and itchiness: Trimethoprim(Bs)