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Minoxidil, when applied topically, is used for the treatment of hair loss. [14] It is effective in helping promote hair growth in people with androgenic alopecia regardless of sex. [14] Minoxidil must be used indefinitely for continued support of existing hair follicles and the maintenance of any experienced hair regrowth. [6] [7]
Minoxidil sulfate is formed from minoxidil via sulfotransferase enzymes, with the predominant enzyme responsible, at least in hair follicles, being SULT1A1. [1] [2] Minoxidil sulfate acts as a potassium channel opener, among other actions, and has vasodilating, hypotensive, and trichogenic or hypertrichotic (hair growth-promoting) effects.
Radiation induces hair loss through damage to hair follicle stem cell progenitors and alteration of keratin expression. [72] [73] Radiation therapy has been associated with increased mucin production in hair follicles. [74] Studies have suggested electromagnetic radiation as a therapeutic growth stimulant in alopecia. [75]
Minoxidil is an effective, FDA-approved treatment for hair loss. But to recap, here’s what you need to know about potential Rogaine interactions: Like any medication, minoxidil can interact with ...
Topical minoxidil is known to prolong the anagen phase, enhance hair length, and prevent telogen effluvium as a therapeutic intervention; nevertheless, therapy is debatable and may not be required, at least in young children.
Pattern hair loss (also known as androgenetic alopecia (AGA) [1]) is a hair loss condition that primarily affects the top and front of the scalp. [2] [3] In male-pattern hair loss (MPHL), the hair loss typically presents itself as either a receding front hairline, loss of hair on the crown and vertex of the scalp, or a combination of both.