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Cerebrospinal fluid (CSF) is a clear, colorless body fluid found within the tissue that surrounds the brain and spinal cord of all vertebrates. CSF is produced by specialized ependymal cells in the choroid plexus of the ventricles of the brain, and absorbed in the arachnoid granulations .
The cerebrospinal fluid (CSF) within the skull and spine provides further protection and also buoyancy, and is found in the subarachnoid space between the pia mater and the arachnoid mater. [citation needed] The CSF that is produced in the ventricular system is also necessary for chemical stability, and the provision of nutrients needed by the ...
For more than a century the prevailing hypothesis was that the flow of cerebrospinal fluid (CSF), which surrounds, but does not come in direct contact with the parenchyma of the CNS, could replace peripheral lymphatic functions and play an important role in the clearance of extracellular solutes. [23]
The blood–cerebrospinal fluid barrier (BCSFB) is a fluid–brain barrier that is composed of a pair of membranes that separate blood from CSF at the capillary level and CSF from brain tissue. [14] The blood–CSF boundary at the choroid plexus is a membrane composed of epithelial cells and tight junctions that link them. [ 14 ]
CSF circulates in the subarachnoid space (between arachnoid and pia mater). Cerebrospinal fluid is produced by the choroid plexus (inside the ventricles of the brain, which are in direct communication with the subarachnoid space so the CSF can flow freely through the nervous system). Cerebrospinal fluid is a transparent, colourless fluid and it ...
The most important substances that are confined to the capillary tube are plasma albumin, the plasma globulins and fibrinogen. They, and particularly the plasma albumin, because of its molecular abundance in the plasma, are responsible for the so-called "oncotic" or "colloid" osmotic pressure which draws water back into the capillary ...
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Lining the CSF-filled ventricles, and spinal canal, the ependymal cells play an important role in the production and regulation of CSF. Their apical surfaces are covered in a layer of cilia, which circulate CSF around the CNS. [4] Their apical surfaces are also covered with microvilli, which absorb CSF.