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Diagram. The technique was first described by Semisotnov et al. (1991) [14] using 1,8-ANS and quartz cuvettes. 3 Dimensional Pharmaceuticals were the first to describe a high-throughput version using a plate reader [15] and Wyeth Research published a variation of the method with SYPRO Orange instead of 1,8-ANS. [16]
Planck was able to calculate the value of from experimental data on black-body radiation: his result, 6.55 × 10 −34 J⋅s, is within 1.2% of the currently defined value. [2] He also made the first determination of the Boltzmann constant k B {\displaystyle k_{\text{B}}} from the same data and theory.
NanoDSF is a type of differential scanning fluorimetry (DSF) method used to determine conformational protein stability by employing intrinsic tryptophan or tyrosine fluorescence, as opposed to the use of extrinsic fluorogenic dyes that are typically monitored via a qPCR instrument. [1] A nanoDSF assay is also known as a type of Thermal Shift Assay.
Differential scanning calorimetry (DSC) is a thermoanalytical technique in which the difference in the amount of heat required to increase the temperature of a sample and reference is measured as a function of temperature. [1]
Architects and engineers call the resulting values either the U-Value or the R-Value of a construction assembly like a wall. Each type of value (R or U) are related as the inverse of each other such that R-Value = 1/U-Value and both are more fully understood through the concept of an overall heat transfer coefficient described in lower section ...
Fig. 1. HSL (a–d) and HSV (e–h). Above (a, e): cut-away 3D models of each. Below: two-dimensional plots showing two of a model's three parameters at once, holding the other constant: cylindrical shells (b, f) of constant saturation, in this case the outside surface of each cylinder; horizontal cross-sections (c, g) of constant HSL lightness or HSV value, in this case the slices halfway ...
The Hildebrand solubility parameter is the square root of the cohesive energy density: =. The cohesive energy density is the amount of energy needed to completely remove a unit volume of molecules from their neighbours to infinite separation (an ideal gas).
HLB scale showing classification of surfactant function. The hydrophilic–lipophilic balance (HLB) of a surfactant is a measure of its degree of hydrophilicity or lipophilicity, determined by calculating percentages of molecular weights for the hydrophilic and lipophilic portions of the surfactant molecule, as described by Griffin in 1949 [1] [2] and 1954. [3]