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Stada. Ketoconazole, sold under the brand name Nizoral, among others, is an antiandrogen, antifungal, and antiglucocorticoid medication used to treat a number of fungal infections. [11] Applied to the skin it is used for fungal skin infections such as tinea, cutaneous candidiasis, pityriasis versicolor, dandruff, and seborrheic dermatitis. [12]
Ketoconazole is an antifungal medication FDA-approved to treat several infections affecting the skin (including the scalp), like athlete’s foot or ringworm. Limited research suggests it may help ...
Stada Arzneimittel AG is a pharmaceutical company based in Bad Vilbel, Germany which specializes on a three-pillar strategy consisting of consumer healthcare products (over-the-counter drugs), generics and specialty pharma. Worldwide, STADA Arzneimittel AG sells its products in approximately 120 countries.
Levoketoconazole is the levorotatory or (2S,4R) enantiomer of ketoconazole, [4] [5] [6] and it is an inhibitor of the enzymes CYP11B1 (11β-hydroxylase), ...
Hemofarm a.d. (full legal name: Hemofarm a.d. Farmaceutsko-hemijska industrija Vršac), a member of STADA Group, is a Serbian pharmaceutical company based in Vršac, Serbia. Founded in 1960, it is one of the largest domestic producer and exporter of medicines in Serbia. Hemofarm currently operates in more than 30 countries on 3 continents and ...
Terconazole synthesis synologous with ketoconazole except for the fact that triazole and not imidazole heterocyclic ring is used, and that isopropyl group instead of acetamide. Terconazole synthesis: U.S. patent 4,144,346 U.S. patent 4,223,036 [12] DE 2804096 Terconazole has the chemical formula C 26 H 31 Cl 2 N 5 O 3.
Concomitant use of prednisolone and strong CYP3A4 inhibitors such as ketoconazole is shown to cause a rise in plasma prednisolone concentrations by about 50% owing to a diminished clearance. [47] Prednisolone predominantly undergoes kidney elimination and is excreted in the urine as sulphate and metabolites of glucuronide conjugate. [14]
Posaconazole is absorbed within three to five hours. It is predominantly eliminated through the liver, and has a half-life of about 35 hours. Oral administration of posaconazole taken with a high-fat meal exceeds 90% bioavailability and increases the concentration by four times compared to fasting state.