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Childhood cataracts are hereditary in 8.3% to 25% of cases. [4] Of which, 75% of cases are inherited in an autosomal dominant fashion. [4] The diagnosis of childhood cataracts are associated with other eye abnormalities in 27% of cases and associated with systemic abnormalities/findings in 22% of cases. [4]
Congenital cataracts are considered to be a significant cause of childhood blindness. This condition is considered 'treatable' with early intervention and compared to other types of childhood visual loss problems, however, in parts of the world where treatment options are not available such as some low-income countries, the condition may go ...
A cataract is a cloudy area in the lens of the eye that leads to a decrease in vision of the eye. [1] [7] Cataracts often develop slowly and can affect one or both eyes. [1] Symptoms may include faded colours, blurry or double vision, halos around light, trouble with bright lights, and difficulty seeing at night. [1]
One common indicator of CTX is cataract that develops in childhood. [7] It has been highlighted that this is an early symptom that comes before neurological symptoms and tendon xanthoma, and it is thought to be helpful for an early diagnosis. [2] Adults with CTX frequently have cataracts and optic disk paleness as well. [8]
Congenital cataract is a lens transparency disorder that occurs at birth or soon after. It is a leading cause of treatable vision loss or visual impairment in children. [2] A cataract is a clouding of the eye's lens. and is caused by a disruption in the normal structure or function of the lens protein, resulting in opacity.
Consequently, today cataracts are more common among adults than in children. [56] That is, people face higher chances of developing cataracts as they age. Nonetheless, cataracts tend to have a greater financial and emotional toll upon children as they must undergo expensive diagnosis, long term rehabilitation, and visual assistance. [58]