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This is a timeline of the development of prophylactic human vaccines. Early vaccines may be listed by the first year of development or testing, but later entries usually show the year the vaccine finished trials and became available on the market. Although vaccines exist for the diseases listed below, only smallpox has
The smallpox vaccine is used to prevent smallpox infection caused by the variola virus. [10] It is the first vaccine to have been developed against a contagious disease. In 1796, British physician Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox virus.
The resulting vaccine was given to about 2,000 children. [12] Many other vaccines, including those for chicken pox and rubella, are made using cell lines originally derived from fetal tissue from two pregnancies terminated in the 1960s, for reasons unrelated to vaccine development.
In February 2020, the World Health Organization (WHO) said it did not expect a vaccine against SARS‑CoV‑2 to become available in less than 18 months. [9] Virologist Paul Offit commented that, in hindsight, the development of a safe and effective vaccine within 11 months was a remarkable feat. [10]
This is an accepted version of this page This is the latest accepted revision, reviewed on 8 January 2025. Administration of a vaccine to protect against disease This article is about administration of a vaccine. For the vaccines themselves, see vaccine. See also: Immunization Medical intervention Vaccinations Girl about to be vaccinated in her upper arm ICD-9-CM 99.3 - 99.5 [edit on Wikidata ...
Boron oxide may refer to one of several oxides of boron: Boron trioxide (B 2 O 3, diboron trioxide), the most common form; Boron monoxide (BO) Boron suboxide (B 6 O)
Commonly available barium metaborate pigment comes in three grades; Grade I is a barium metaborate itself, grade II is compounded with 27% zinc oxide, and grade III is compounded with 18% of zinc oxide and 29% calcium sulfate. Barium borate shows synergistic performance with zinc borate. [17]
The first plague vaccine was developed by bacteriologist Waldemar Haffkine in 1897. [3] [4] He tested the vaccine on himself to prove that the vaccine was safe.[4] [5] Later, Haffkine conducted a massive inoculation program in British India, and it is estimated that 26 million doses of Haffkine's anti-plague vaccine were sent out from Bombay between 1897 and 1925, reducing the plague mortality ...