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Nelson claims that relative to marijuana, products containing synthetic cannabinoids "are really quite different, and the effects are much more unpredictable. It's dangerous". [47] Since the term synthetic does not apply to the plant, but rather to the cannabinoid that the plant contains , the term synthetic cannabinoid is more appropriate. [48]
Dimethylheptylpyran (DMHP) is a synthetic cannabinoid and analogue of tetrahydrocannabinol (THC). It was invented in 1949 during attempts to elucidate the structure of Δ 9-THC, one of the active components of cannabis. [2] DMHP is a pale yellow, viscous oil which is insoluble in water but dissolves in alcohol or non-polar solvents.
HU-210 is a synthetic cannabinoid that was first synthesized in 1988 from (1R,5S)-myrtenol [2] by a group led by Raphael Mechoulam at the Hebrew University. [3] [4] [5] HU-210 is 100 to 800 times more potent than natural THC from cannabis and has an extended duration of action. [6]
Synthetic marijuana, commonly called "K2" or "spice," is especially popular in prison systems and jails across the country because it's cheap, easy to smuggle, and doesn't show up in routine urine ...
Synthetic cannabinoids are particularly useful in experiments to determine the relationship between the structure and activity of cannabinoid compounds, by making systematic, incremental modifications of cannabinoid molecules. [99] When synthetic cannabinoids are used recreationally, they present significant health dangers to users. [100]
Synthetic cannabinoids are known under a variety of names including K2, Spice, Black Mamba, Bombay Blue, Genie, Zohai, [38] Banana Cream Nuke, Krypton, and Lava Red. [39] They are often called "synthetic marijuana," "herbal incense," or "herbal smoking blends" and often labeled "not for human consumption." [38]
Tetrahydrocannabiphorol (THCP) is a potent phytocannabinoid, a CB 1 and CB 2 receptor agonist which was known as a synthetic homologue of tetrahydrocannabinol (THC), [1] but for the first time in 2019 was isolated as a natural product in trace amounts from Cannabis sativa. [2] [3]
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