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Likewise, many intersex individuals are born completely sterile, although medical interventions have been known to remove potentially fertile gonads, which makes sex determination often arbitrary. Individuals with XX male develop male genitalia but are entirely infertile due to a lack of SRY gene expression and develop a generally feminine body.
[1] [2] Such variations may involve genital ambiguity, and combinations of chromosomal genotype and sexual phenotype other than XY-male and XX-female. [ 3 ] [ 4 ] Preimplantation genetic diagnosis allows the elimination of embryos and fetuses with intersex traits and thus has an impact on discrimination against intersex people.
This is an accepted version of this page This is the latest accepted revision, reviewed on 5 January 2025. Atypical congenital variations of sex characteristics This article is about intersex in humans. For intersex in other animals, see Intersex (biology). Not to be confused with Hermaphrodite. Intersex topics Human rights and legal issues Compulsory sterilization Discrimination Human rights ...
The embryo and subsequent early fetus appear to be sexually indifferent, looking neither like a male or a female. Over the next several weeks, hormones are produced that cause undifferentiated tissue to transform into either male or female reproductive organs. This process is called sexual differentiation.
XX male syndrome, also known as de la Chapelle syndrome, is a rare intersex condition in which an individual with a 46,XX karyotype develops a male phenotype. [2] Synonyms for XX male syndrome include 46,XX testicular difference of sex development (or 46,XX DSD) [3] [4] [5] [6]
Complete androgen insensitivity syndrome causes a genetic male to have a vagina (often incompletely developed, nearly always blind-ending), breasts, and a clitoris; people with this form are raised as females. [25] Aphallia – a rare condition where a XY male is born without a penis. As of 2017, only 100 cases have been reported in literature ...
As of 2010, there have been at least 11 reported cases of fertility in humans with ovotesticular syndrome in the scientific literature, [4] with one case of a person with XY-predominant (96%) mosaic giving birth. [30] All known offspring have been male. [31] There has been at least one case of an individual being fertile as a male. [28]
The pelvis is, in general, different between the human female and male skeleton. [12] [13] Although variations exist and there may be a degree of overlap between typically male or female traits, [12] [13] the pelvis is the most dimorphic bone of the human skeleton and is therefore likely to be accurate when using it to ascertain a person's sex ...