Search results
Results From The WOW.Com Content Network
Advantages of cluster-randomised controlled trials over individually randomised controlled trials include: The ability to study interventions that cannot be directed toward selected individuals (e.g., a radio show about lifestyle changes) and the ability to control for "contamination" across individuals (e.g., one individual's changing behaviors may influence another individual to do so).
The Alliance for Clinical Trials in Oncology is a national clinical trials network sponsored by the National Cancer Institute (NCI) that consists of about 10,000 cancer specialists at hospitals, medical centers, and community clinics across the United States and Canada. [1]
[1] [2] The crossover is in one direction, typically from control to intervention, with the intervention not removed once implemented. The stepped-wedge design can be used for individually randomized trials, [3] [4] i.e., trials where each individual is treated sequentially, but is more commonly used as a cluster randomized trial (CRT). [5]
The DRKS is an open access, free of charge online register for clinical trials and is available both in English and German. DRKS is part of the WHO's ICTRP. The DRKS works with two partner registries in Germany, DeReG (German Registry for Somatic Gene-Transfer Trials) and Clinical Trial Registry of the University Medical Center Freiburg. [4]
A 2013 study analyzing 8907 interventional trials registered in ClinicalTrials.gov found that 23.2% of trials had abstract-linked result articles and 7.3% of trials had registry-linked articles. 2.7% of trials had both types of links. Most trials are linked to a single result article (76.4%). [24]
After years of work, Himmelfarb and Ratner brought their revolutionary new dialysis device, called AKTIV (Ambulatory Kidney to Increase Vitality), just inches from clinical trials.
In 2024, Prasad expressed criticism for the funding decisions of the NIH as well as support for more cluster randomized controlled trials. [38] However, according to physician David Gorski, Prasad again demonstrated insufficient understanding of the limitations of these randomized controlled trials as well as how the NIH's funding decisions ...
The main CONSORT Statement is based on the "standard" two-group parallel design. Extensions of the CONSORT Statement have been developed to give additional guidance for randomized trials with specific designs (e.g., cluster randomized trials, [3] noninferiority and equivalence trials, [4] pragmatic trials [5]), data (e.g., harms, [6] abstracts [7]), type of target outcome, [8] and various ...