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The central dogma of molecular biology deals with the flow of genetic information within a biological system. It is often stated as "DNA makes RNA, and RNA makes protein", [1] although this is not its original meaning. It was first stated by Francis Crick in 1957, [2] [3] then published in 1958: [4] [5] The Central Dogma.
Darwinism subsequently referred to the specific concepts of natural selection, the Weismann barrier, or the central dogma of molecular biology. [2] Though the term usually refers strictly to biological evolution, creationists have appropriated it to refer to the origin of life or to cosmic evolution, that are distinct to biological evolution, [3] and therefore consider it to be the belief and ...
John Maynard Smith. The formulation of the central dogma of molecular biology was summarized by Maynard Smith: . If the central dogma is true, and if it is also true that nucleic acids are the only means whereby information is transmitted between generations, this has crucial implications for evolution.
This image shows an example of the central dogma using a DNA strand being transcribed then translated and showing important enzymes used in the processes. The central dogma plays a key role in the study of molecular genetics. The central dogma states that DNA replicates itself, DNA is transcribed into RNA, and RNA is translated into proteins. [24]
Developmental systems theory, by contrast, assumes that the process/data distinction is at best misleading and at worst completely false, and that while it may be helpful for very specific pragmatic or theoretical reasons to treat a structure now as a process and now as a datum, there is always a risk (to which reductionists routinely succumb ...
The "central dogma of molecular biology" (originally a "dogma" only in jest) was proposed by Francis Crick in 1958. [78] This is Crick's reconstruction of how he conceived of the central dogma at the time. The solid lines represent (as it seemed in 1958) known modes of information transfer, and the dashed lines represent postulated ones.
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The extended central dogma of molecular biology includes all the processes involved in the flow of genetic information. Main article: Gene expression Gene expression is the molecular process by which a genotype encoded in DNA gives rise to an observable phenotype in the proteins of an organism's body.