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The mechanical stress of heavy structural strain causes this stratum lucidum phase in these regions which require additional protection in order to grasp objects, resist abrasion or impact, and avoid injury. In general, the stratum corneum contains 15 to 20 layers of corneocytes. The stratum corneum has a thickness between 10 and 40 μm.
Dry skin involves increased thickness of stratum corneum (hyperkeratosis), which may occur due to various reasons including aging, humidity of the environment or UV irradiation. The accumulation of corneocyte clumps on the surface of the skin may lead to abnormal detachment of squames as visible clusters.
Hyperkeratosis is thickening of the stratum corneum (the outermost layer of the epidermis, or skin), often associated with the presence of an abnormal quantity of keratin, [1] and is usually accompanied by an increase in the granular layer. As the corneum layer normally varies greatly in thickness in different sites, some experience is needed ...
2D projection of a 3D OCT-tomogram of the skin at the fingertip, depicting the stratum corneum (≈500 μm thick) with the stratum disjunctum on top and the stratum lucidum in the middle. At the bottom are the superficial parts of the dermis. The sweat ducts are clearly visible. (See also: Rotating 3D Version)
The thickness of the epidermis varies from 31.2μm for the penis to 596.6μm for the sole of ... Confocal image of the stratum corneum Composed of 10 to 30 layers ...
The stratum corneum is the top layer of the skin and varies in thickness from approximately ten to several hundred micrometres, depending on the region of the body. [1] It is composed of layers of dead, flattened keratinocytes surrounded by a lipid matrix, which together act as a brick-and-mortar system that is difficult to penetrate.
With the advancement of tissue engineering an alternative approach was developed: the full-thickness engineered oral mucosa. Full-thickness engineered oral mucosa is a better simulation of the in vivo situation because they take the anatomical structure of native oral mucosa into account. Problems, such as tissue shortage and donor site ...
Scale forms on the skin surface in various disease settings, and is the result of abnormal desquamation. In pathologic desquamation, such as that seen in X-linked ichthyosis, the stratum corneum becomes thicker (hyperkeratosis), imparting a "dry" or scaly appearance to the skin, and instead of detaching as single cells, corneocytes are shed in clusters, which forms visible scales. [2]