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  2. Post-exertional malaise - Wikipedia

    en.wikipedia.org/wiki/Post-exertional_malaise

    It is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and common in long COVID and fibromyalgia. [3] [1] PEM is often severe enough to be disabling, and is triggered by ordinary activities that healthy people tolerate. Typically, it begins 12–48 hours after the activity that triggers it, and lasts for days ...

  3. Fibromyalgia - Wikipedia

    en.wikipedia.org/wiki/Fibromyalgia

    Fibromyalgia was first defined in 1990, with updated criteria in 2011, [4] 2016, [9] and 2019. [12] Fibromyalgia is estimated to affect 2 to 4% of the population. [13] Women are affected more than men. [4] [13] Rates appear similar across areas of the world and among varied cultures. [4] Symptoms of fibromyalgia are persistent in nearly all ...

  4. Management of ME/CFS - Wikipedia

    en.wikipedia.org/wiki/Management_of_ME/CFS

    Graded exercise therapy (GET) is a programme of physical activity that starts very slowly and gradually increases over time in fixed increments. Most public health bodies, including the CDC and NICE, consider it ineffective, and its safety is disputed. [35] [36] [37] In particular, NICE removed their recommendation for this treatment in 2021.

  5. Clinical descriptions of ME/CFS - Wikipedia

    en.wikipedia.org/wiki/Clinical_descriptions_of...

    Celiac disease screening; Urinalysis for blood cells, protein and glucose; In addition to the CDC's recommendation, the NICE guideline recommends HbA1c and creatine kinase tests, and mentions that blood tests for vitamins D and B 12, infectious diseases, and adrenal insufficiency may be warranted. [18]

  6. National Fibromyalgia Association - Wikipedia

    en.wikipedia.org/wiki/National_Fibromyalgia...

    The National Fibromyalgia Association (NFA) is a nonprofit organization whose purpose is to help improve the quality of life for people living with fibromyalgia (FM) and other chronic pain conditions. The NFA has worked to build international awareness of this chronic pain disorder, provide patient assistance and support, educate the medical ...

  7. National Institute for Health and Care Excellence - Wikipedia

    en.wikipedia.org/wiki/National_Institute_for...

    The Guideline Development Group then finalises the recommendations and the National Collaboration Centre produces the final guideline. This is submitted to NICE to formally approve the guideline and issue the guidance to the NHS. [citation needed] To date NICE has produced more than 200 different guidelines. [28]

  8. Controversies related to ME/CFS - Wikipedia

    en.wikipedia.org/wiki/Controversies_related_to...

    Despite ample evidence that ME/CFS is an organic disease, many clinicians do not recognise it as genuine or underestimate its seriousness. [8] [5] [6] A 2020 literature review found that “a third to a half of all GPs did not accept ME/CFS as a genuine clinical entity and, even when they did, they lacked confidence in diagnosing or managing it.” [6]

  9. Myalgic encephalomyelitis/chronic fatigue syndrome - Wikipedia

    en.wikipedia.org/wiki/Myalgic_encephalomyelitis/...

    In addition, drug companies have invested very little in the disease. [94] The US National Institutes of Health (NIH) is the largest biomedical funder worldwide. [95] Using rough estimates of disease burden, a study found NIH funding for ME/CFS was only 3% to 7% of the average disease per healthy life year lost between 2015 and 2019. [96]