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An ongoing Phase 2 trial in 2016 presented data [164] showing that after 90 days, 2 out of 4 subjects had already improved two motor levels and had thus already achieved its endpoint of 2/5 patients improving two levels within 6–12 months. Six-month data was expected in January 2017. [165]
The spinal cord and the brain work together, making them the key components of the central nervous system. [5] Damage to this system affects specific functions of the body, primarily relating to the function of muscles. The areas most commonly injured include the cervical vertebrae (C1-C7), and the lumbar spine (L1-L5). [6]
A syrinx may also cause disruptions in the parasympathetic and sympathetic nervous systems, leading to Horner syndrome, abnormal body temperature or sweating, bowel control issues, or other problems. If the syrinx is higher up in the spinal cord or affecting the brainstem, as in syringobulbia, vocal cord paralysis , ipsilateral tongue wasting ...
It is a neurological and orthopedic condition that affects the motor nervous system of the body, specifically, the lower back, legs, hips and glutes. [ 5 ] [ 6 ] NC does not occur by itself, but rather, is associated with other underlying spinal or neurological conditions such as spinal stenosis or abnormalities and degenerative changes in the ...
Lumbar spinal stenosis (LSS) is a medical condition in which the spinal canal narrows and compresses the nerves and blood vessels at the level of the lumbar vertebrae. Spinal stenosis may also affect the cervical or thoracic region, in which case it is known as cervical spinal stenosis or thoracic spinal stenosis.
An MRI of the lumbar spine with abscess that resulted in CES. Cauda equina syndrome is a rare syndrome that affects the spinal nerves in the region of the lower back called the cauda equine (Latin for "horses tail"). Injury to the cauda equina can have long lasting ramifications for the individual.