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Use of anticonvulsant medications should be carefully monitored during use in pregnancy. [94] For example, since the first trimester is the most susceptible period for fetal development, planning a routine antiepileptic drug dose that is safer for the first trimester could be beneficial to prevent pregnancy complications. [95]
Children should be treated with proper and effective therapy to prevent irreversible neural damage. [5] Treatment options for epilepsy include medications, diet, and surgery. [6] Diet and surgery are considered for children who have medication resistant epilepsy. [7]
Common anticonvulsants used to treat neuropathy are gabapentinoids (calcium channel blockers) and carbamazapine (sodium channel blocker). [8] There is some evidence that anticonvulsants may also help with inflammatory pain through reduction of nociceptor hyper-excitability originally due to damage to surrounding tissue.
Studies for the use of ESL as an anticonvulsant for children are under way as of 2016. [16] Like oxcarbazepine, ESL has potential uses for the treatment of trigeminal neuralgia [citation needed] and bipolar disorder. A 2015 assessment showed no statistical difference to placebo for the latter disorder. [17]
Depakote (valproic acid/sodium valproate) – an antiepileptic and mood stabilizer used to treat bipolar disorder, neuropathic pain and others; sometimes called an antimanic medication. Depakene is the trade name for the same drug prepared without sodium. Desyrel – an atypical antidepressant used to treat depression and insomnia
About 20% of children on the ketogenic diet achieve freedom from seizures, and many are able to reduce the use of anticonvulsant drugs or eliminate them altogether. [18] Commonly, at around two years on the diet, or after six months of being seizure-free, the diet may be gradually discontinued over two or three months.
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