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This suggests that the limbic system, which forms part of the dopamine reward pathway, is most involved in making impulsive decisions while the cortex is responsible for the more general aspects of the intertemporal decision process. [38] [39] The neurotransmitter serotonin seems to play an important role in modulating future discounting.
The limbic system operates by influencing the endocrine system and the autonomic nervous system. It is highly interconnected with the nucleus accumbens , which plays a role in sexual arousal and the "high" derived from certain recreational drugs .
However, there has not been additional proof of the circuit's role in emotion over the years. Now, the Amygdala is thought to play a key role in emotion, a structure that was not a part of the Papez circuit until 1952 when MacLean included it in the modified version of the circuit, the limbic system.
Eysenck's three-factor model of personality was a causal theory of personality based on activation of reticular formation and limbic system. The reticular formation is a region in the brainstem that is involved in mediating arousal and consciousness. The limbic system is involved in mediating emotion, behavior, motivation, and long-term memory.
The output neurons of the nucleus accumbens send axonal projections to the basal ganglia and the ventral analog of the globus pallidus, known as the ventral pallidum (VP). ). The VP, in turn, projects to the medial dorsal nucleus of the dorsal thalamus, which projects to the prefrontal cortex as well as back to the ventral and to dorsal stri
The mesolimbic pathway and a specific set of the pathway's output neurons (e.g. D1-type medium spiny neurons within the nucleus accumbens) play a central role in the neurobiology of addiction. [20] [21] [22] Drug addiction is an illness caused by habitual substance use that induces chemical changes in the brain's circuitry. [23]
The hypothalamus also influences daily physiologic cycles and plays a role in regulating emotional responses. Many of these functions can be described as homeostatic . It is the most ventral part of the diencephalon and contains three regions: the supraoptic region, the tuberal region, and the mammillary region.
This area is important in memory and planning. Posterior association area: Located in the posterior parietal lobe. [6] This area plays an important role in perception and language. Damage to this area can result in agnosia. Limbic association area: Located in the anterior-ventral portion of the temporal lobe, this area links emotion with ...