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Good glycemic control, in the sense of a "target" for treatment, has become an important goal of diabetes care. Poor glycemic control refers to persistently (over several months) elevated BG in the 200 to 500 mg/dL (11–28 mmol/L). This is also measured by Hb A1c levels, which may range from greater than 9%.
A1c is of particular interest because it is easy to detect. The process by which sugars attach to hemoglobin is called glycation and the reference system is based on HbA1c, defined as beta-N-1-deoxy fructosyl hemoglobin as component. [4] There are several ways to measure glycated hemoglobin, of which HbA1c (or simply A1c) is a standard single ...
Normal A1C for people without diabetes is below 5.6 percent, Dr. Peterson says. Levels between 5.7 percent and 6.5 percent suggest prediabetes, and an A1C of 6.5 percent or higher puts you in the ...
Healthcare providers can also monitor someone's hemoglobin A1C levels which reflect the average blood sugar over the last three months. [51] The American Diabetes Association recommends a goal of keeping hemoglobin A1C levels under 7% for most adults and 7.5% for children. [51] [52]
[107] [109] The goal of treatment is an A1C level below 7%. [110] [111] Attention is also paid to other health problems that may accelerate the negative effects of diabetes. These include smoking, high blood pressure, metabolic syndrome obesity, and lack of regular exercise.
A combined result of 5 RCTs enlisting a total of 238 patients aged 65 or older (mean baseline HbA1c of 8.6%) receiving 100 mg/d of vildagliptin was shown to reduce HbA1c by 1.2%. [46] Another set of 6 combined RCTs involving alogliptin (approved by FDA in 2013) was shown to reduce HbA1c by 0.73% in 455 patients aged 65 or older who received 12. ...