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English: ThymiStem in collaboration with animator Cameron Duguid have created a beautiful, hand drawn animation explaining the function of the thymus, an essential organ of the immune system. The video shows how T cells, a type of white blood cell, go through a complex journey in the thymus to become mature immune cells ready to fight off ...
Kathy Smith (born December 11, 1951) [2] is an American personal trainer who became well known for her workout videos during the late 1980s and 1990s. She has sold over 16 million workout videos since 1980. [3] Her exercise and nutrition program Project:You!
The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. [5] It is a 13kbp gene on chromosome 21q22.3 that encodes 545 amino acids. [6] AIRE is a transcription factor expressed in the medulla [broken anchor] (inner part) of the thymus.
TECs, as a component of the thymus, play a key role in thymocyte development and self-tolerance, so their dysfunction causes many autoimmune diseases, tumors of immunodeficiencies. Most frequently are occurred epithelial tumors established from TEC and thymocytes - thymomas and thymic carcinoma.
While cTECs control the functionality of TCRs during the process called positive selection, Medullary thymic epithelial cells (mTECs) that home in the inner part of the thymus- medulla, present on their MHC molecules self-peptides, generated mostly by protein Autoimmune regulator, to eliminate T cells with self-reactive TCRs via processes of ...
In 1989, two scientific groups came up with the hypothesis that the thymus expresses genes which are in the periphery, strictly expressed by specific tissues (e.g.: Insulin produced by β cells of the pancreas) to subsequently present these so-called "tissue-restricted antigens" (TRAs) from almost all parts of the body to developing T cells in order to test which TCRs recognize self-tissues ...
School children perform sit-ups, a common type of calisthenic, during a school fitness day.. Calisthenics (American English) or callisthenics (British English) (/ ˌ k æ l ɪ s ˈ θ ɛ n ɪ k s /) is a form of strength training that utilizes an individual's body weight as resistance to perform multi-joint, compound movements with little or no equipment.
Functional Strength Training is a fitness approach designed to enhance the body's ability to perform everyday movements with ease and efficiency. Unlike traditional strength training that isolates specific muscle groups, functional training focuses on exercises that mimic real-life activities, such as lifting, squatting, and climbing.