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Cerebral softening, also known as encephalomalacia, is a localized softening of the substance of the brain, due to bleeding or inflammation. Three varieties, distinguished by their color and representing different stages of the disease progress, are known respectively as red, yellow, and white softening.
The name of the condition includes the word "posterior" because it predominantly, though not exclusively, affects the back of the brain (the parietal and occipital lobes). Common underlying causes are severely elevated blood pressure , kidney failure , severe infections , certain medications, some autoimmune diseases , and pre-eclampsia .
[1] [4] The disease often gets worse over time and can result in dementia. [ 2 ] Most documented cases have occurred in athletes involved in striking -based combat sports , such as boxing , kickboxing , mixed martial arts , and contact sports such as rugby union , rugby league , American football , Australian rules football , professional ...
It is important to differentiate PVL from the following major white matter lesions in the cerebral hemispheres: edematous hemorrhagic leukoencephalopathy (OGL), telentsefalny gliosis (TG), diffuse leukomalacia (DFL), subcortical leukomalacia (SL), periventricular hemorrhagic infarction (PHI), intracerebral hemorrhage ( ICH), multicystic ...
Porencephaly is an extremely rare cephalic disorder involving encephalomalacia. [1] It is a neurological disorder of the central nervous system characterized by cysts or cavities within the cerebral hemisphere. [2] Porencephaly was termed by Heschl in 1859 to describe a cavity in the human brain. [3]
Malacia is abnormal softening of a biological tissue, most often cartilage.The word is derived from Greek μαλακός, malakos = soft. Usually the combining form-malacia suffixed to another combining form that denotes the affected tissue assigns a more specific name to each such disorder, as follows:
However, the prognosis of toxic leukoencephalopathy is typically slightly worse than that of PRES because toxic leukoencephalopathy is more likely to lead to ataxia, dementia, or coma. [ 4 ] Hypoglycemic encephalopathy is often seen in diabetics as a result to accidental overdose with the long-acting sulfonylurea drug group. [ 12 ]
Wallerian degeneration is named after Augustus Volney Waller.Waller experimented on frogs in 1850, by severing their glossopharyngeal and hypoglossal nerves. He then observed the distal nerves from the site of injury, which were separated from their cell bodies in the brain stem. [5]